David Thomas

Associate Professor



720-848-0134


Department of Radiation Oncology

University of Colorado Anschutz Medical Campus

Department of Radiation Oncology – University of Colorado Denver | Anschutz Medical Campus
1665 Aurora Court, Suite 1032
Mail Stop F706
Aurora, CO 80045



Publications


Computer Vision assisted Collision Avoidance for Radiation Therapy


David Thomas, Moyed Miften, Brian Kavanagh, Bernard Trip Jones,

2023 May



Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy


Farnoush Forghani, Taylor Patton, Jennifer Kwak, David Thomas, Quentin Diot, Chad Rusthoven, Richard Castillo, Edward Castillo, Inga Grills, Thomas Guerrero, others

Radiotherapy and Oncology, vol. 160, Elsevier, 2021, pp. 120--124



Analysis of experimental acoustic waves induced by high energy pulsed X-ray beams


Farnoush Forghani, Adam Mahl, Bernard Jones, Mark Borden, Moyed Miften, David Thomas

Bulletin of the American Physical Society, vol. 65, APS, 2020



Simulation of x-ray-induced acoustic imaging for absolute dosimetry: Accuracy of image reconstruction methods


Farnoush Forghani, Adam Mahl, Taylor J Patton, Bernard L Jones, Mark A Borden, David C Westerly, Cem Altunbas, Moyed Miften, David H Thomas

Medical Physics, vol. 47, Wiley Online Library, 2020, pp. 1280--1290



Effect of X-Ray Irradiation On the Ultrasound Imaging Signal of a Novel Photoacoustic Contrast Agent


F Forghani, A Mahl, G Shakya, M Borden, T Patton, Y Vinogradskiy, B Jones, M Miften, D Thomas

MEDICAL PHYSICS, vol. 47, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2020, pp. E763--E763



Lung Functional Avoidance Radiotherapy: Characterizing Spatial Differences Between Ventilation and Perfusion


F Forghani, T Patton, D Thomas, Q Diot, C Rusthoven, R Castillo, E Castillo, I Grills, T Guerrero, M Miften, others

MEDICAL PHYSICS, vol. 47, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2020, pp. E370--E370



A fast and effective denoising solution using deep learning for real time X-ray Acoustic Computed Tomography


David Thomas, Farnoush Forghani, Adam Mahl, Bernard Jones, Mark Borden, Moyed Miften

Bulletin of the American Physical Society, vol. 65, APS, 2020



Integration of automation into an existing clinical workflow to improve efficiency and reduce errors in the manual treatment planning process for total body irradiation (TBI)


David H Thomas, Brian Miller, Rachel Rabinovitch, Sarah Milgrom, Brian Kavanagh, Quentin Diot, Moyed Miften, Leah K Schubert

Journal of Applied Clinical Medical Physics, Wiley Online Library, 2020



Deep Learning approach for automatic detection and identification of patient positioning devices for radiation therapy


David H Thomas, Leah K Schubert, Yevgeniy Vinogradskiy, Sameer Nath, Brian Kavanagh, Moyed Miften, Bernard Jones

Medical Physics, Wiley Online Library, 2020



An Analysis of X-Ray Induced Acoustic Imaging and Its Accuracy for Absolute Dosimetry


F Forghani, D Thomas

MEDICAL PHYSICS, vol. 46, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019, pp. E412--E413



Clinical Introduction of 5DCT Simulation for Lung Cancer


M Lauria, D O'Connell, N Agazaryan, J Lewis, J Lamb, D Thomas, P Lee, D Low

MEDICAL PHYSICS, vol. 46, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019, pp. E521--E522



Safety-oriented design of in-house software for new techniques: A case study using a model-based 4 DCT protocol


Dylan O'Connell, David H Thomas, John H Lewis, Katelyn Hasse, Anand Santhanam, James M Lamb, Minsong Cao, Stephen Tenn, Nzhde Agazaryan, Percy P Lee, others

Medical physics, vol. 46, Wiley Online Library, 2019, pp. 1523--1532



An Efficient Workflow for Generation and Refinement of a Knowledge Based Planning Model for Pancreas SBRT Using Automation


T Patton, Q Diot, B Jones, L Olsen, Y Vinogradskiy, K Goodman, T Schefter, D Thomas

MEDICAL PHYSICS, vol. 46, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019, pp. E367--E367



The current state of physics plan review training in medical physics residency programs in North America


Leah K Schubert, Kristi Hendrickson, Moyed Miften, Monica McNulty, Yevgeniy Y Vinogradskiy, David H Thomas, David Westerly, Kelly Stuhr, Janet Corral, Danielle Royer

Practical radiation oncology, Elsevier, 2019



The effect of resonance on transient microbubble acoustic response: Experimental observations and numerical simulations


K Efthymiou, N Pelekasis, MB Butler, DH Thomas, V Sboros

The Journal of the Acoustical Society of America, vol. 143, ASA, 2018, pp. 1392--1406



Model-Interpolated Gating for MRI-Guided Radiotherapy


John S Ginn, Dylan O�Connell, David H Thomas, Daniel A Low, James M Lamb

International Journal of Radiation Oncology� Biology� Physics, Elsevier, 2018



Model-Interpolated Gating for Magnetic Resonance Image--Guided Radiation Therapy


John S Ginn, Dylan O�Connell, David H Thomas, Daniel A Low, James M Lamb

International Journal of Radiation Oncology* Biology* Physics, vol. 102, Elsevier, 2018, pp. 885--894



Is There a Better Way Than 4DCT to Characterize Breathing Motion?


D Low, D O'Connell, D Thomas, T Dou, J Lewis, P Lee

MEDICAL PHYSICS, vol. 45, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018, pp. E363--E363



CBCT-Based Dose Calculations with a Two-Dimensional Anti-Scatter Grid Prototype: The Effect of Scatter Suppression On Dose-Calculation Accuracy


B Miller, T Alexeev, D Thomas, K Stuhr, B Kavanagh, M Miften, C Altunbas

MEDICAL PHYSICS, vol. 45, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018, pp. E151--E151



CBCT-Based Dose Calculations with a Two-Dimensional Anti-Scatter Grid Prototype: The Effect of Scatter Suppression On Dose-Calculation Accuracy


B Miller, T Alexeev, D Thomas, K Stuhr, B Kavanagh, M Miften, C Altunbas

MEDICAL PHYSICS, vol. 45, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018, pp. E151--E151



Safety-Oriented Design of In-House Software for Translating New Techniques From Research to Clinical Practice: A Case Study Using a Model-Based 4DCT Protocol


D O'Connell, D Thomas, J Lewis, N Agazaryan, M Cao, S Tenn, P Lee, D Low

MEDICAL PHYSICS, vol. 45, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018, pp. E523--E523



Safety-Oriented Design of In-House Software for Translating New Techniques From Research to Clinical Practice: A Case Study Using a Model-Based 4DCT Protocol


D O'Connell, D Thomas, J Lewis, N Agazaryan, M Cao, S Tenn, P Lee, D Low

MEDICAL PHYSICS, vol. 45, WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018, pp. E523--E523



A prospective gating method to acquire a diverse set of free-breathing CT images for model-based 4DCT


Dylan O'Connell, Dan Ruan, David H Thomas, Tai H Dou, John H Lewis, Anand P Santhanam, Percy P Lee, Daniel A Low

Physics in Medicine and Biology, 2018



Dependence of subject-specific parameters for a fast helical CT respiratory motion model on breathing rate: an animal study


Dylan O�Connell, David H Thomas, James M Lamb, John H Lewis, Tai Dou, Jered P Sieren, Melissa Saylor, Christian Hofmann, Eric A Hoffman, Percy P Lee, others

Physics in Medicine \& Biology, vol. 63, IOP Publishing, 2018, pp. 04NT04



A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images


J. R. McClelland, M. Modat, S. Arridge, H. Grimes, D. D'Souza, D. H. Thomas, D. O. Connell, D. A. Low, E. Kaza, D. J. Collins, M. O. Leach, D. J. Hawkes

Phys Med Biol, vol. 62, 2017, pp. 4273-4292



Technical Note: Simulation of 4DCT Tumor Motion Measurement Errors


T H Dou, D H Thomas, D O�Connell, J Bradley, D A Low

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, p. 6084



A Method for Assessing Ground-Truth Accuracy of the 5DCT Technique


T H Dou, D H Thomas, D H O�Connell, J M Lamb, P Lee, D A Low

International Journal of Radiation Oncology* Biology* Physics, vol. 93, American Association of Physicists in Medicine, 2015, pp. 925--933



TH-CD-303-04: A Method for Assessing Ground-Truth Accuracy of a Motion Model Based 4DCT Technique


T Dou, D H Thomas, D O�Connell, J Lamb, D Low

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3729--3729



SU-EJ-206: Adaptive Radiotherapy for Gynecological Malignancies with MRIGuided Cobolt-60 Radiotherapy


J Lamb, M Kamrava, N Agazaryan, M Cao, D Low, D H Thomas, Y Yang

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3312--3313



5D respiratory motion model based image reconstruction algorithm for 4D cone-beam computed tomography


Jiulong Liu, Xue Zhang, Xiaoqun Zhang, Hongkai Zhao, Yu Gao, DH Thomas, Daniel Low, Hao Gao

Inverse Problems, vol. 31, IOP, 2015, p. 115007



SU-EJ-234: Application of a Breathing Motion Model to ViewRay Cine MR Images


D P O�Connell, D H Thomas, T H Dou, J M Lamb, L Yang, D A Low

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3319--3319



SU-C-BRA-05: Fast Generation of Respiratory Gated CT Images at User Selected Breathing Phases On a Graphics Processing Unit


D P O�Connell, D H Thomas, TH Dou, J M Lamb, L Yang, D A Low

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3196--3196



Comparison of breathing gated CT images generated using a 5DCT technique and a commercial clinical protocol in a porcine model


Dylan P O�Connell, D H Thomas, Tai H Dou, James M Lamb, Franklin Feingold, Daniel A Low, Matthew K Fuld, Jered P Sieren, Chelsea M Sloan, Melissa A Shirk, others

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 4033--4042



Objective function to obtain multiple representative waveforms for a novel helical CT scan protocol


Dan Ruan, D H Thomas, Daniel A Low

Medical Physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 1164--1169



SU-F-303-17: Real Time Dose Calculation of MRI Guided Co-60 Radiotherapy Treatments On Free Breathing Patients, Using a Motion Model and Fast Monte Carlo Dose Calculation


D H Thomas, D O�Connell, J Lamb, M Cao, Y Yang, N Agazaryan, P Lee, D Low

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3541--3541



TH-CD-204-06: Diffusion MRI for Treatment Response Assessment of MRI-Guided Tri-Cobalt 60 Radiotherapy


Y Yang, D Low, M Cao, K Sheng, J Lamb, D H Thomas, M Kamrava, P Hu

Medical physics, vol. 42, American Association of Physicists in Medicine, 2015, pp. 3733--3733



SU-D-17A-03: 5D Respiratory Motion Model Based Iterative Reconstruction Method for 4D Cone-Beam CT


Y Gao, D H Thomas, D Low, H Gao

Medical Physics, vol. 41, American Association of Physicists in Medicine, 2014, pp. 117--117



Automatic dissociation between microvasculature and larger vessels for ultrasound contrast imaging


Antonios Perperidis, David Thomas, Michalakis Averkiou, Colin Duncan, Alan McNeilly, Mairead Butler, Vassilis Sboros

Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE, IEEE, 2014, pp. 5076--5079



A Novel Fast Helical 4D-CT Acquisition Technique to Generate Low-Noise Sorting Artifact--Free Images at User-Selected Breathing Phases


D H Thomas, James Lamb, Benjamin White, Shyam Jani, Sergio Gaudio, Percy Lee, Dan Ruan, Michael McNitt-Gray, Daniel Low

International Journal of Radiation Oncology* Biology* Physics, vol. 89, Elsevier, 2014, pp. 191--198



TH-C-18A-11: Investigating the Minimum Scan Parameters Required to Generate Free-Breathing Fast-Helical CT Scans Without Motion-Artifacts


D H Thomas, J Tan, J Neylon, T Dou, S Jani, J Lamb, D Low

Medical Physics, vol. 41, American Association of Physicists in Medicine, 2014, pp. 559--559



Modeling and incorporating cardiac?induced lung tissue motion in a breathing motion model


Benjamin M White, Anand Santhanam, David Thomas, Yugang Min, James M Lamb, Jack Neylon, Shyam Jani, Sergio Gaudio, Subashini Srinivasan, Daniel Ennis

Medical physics, vol. 41, 2014



SU-E-J-126: Development of a Prospective Gating Algorithm for a Novel 4DCT Technique: Retrospective Data Analysis


D Low, D H Thomas, B White, S Gaudio, S Jani, P Lee, J Lamb

Medical Physics, vol. 40, American Association of Physicists in Medicine, 2013, pp. 179--179



The acoustic signature of decaying resonant phospholipid microbubbles


DH Thomas, M Butler, N Pelekasis, T Anderson, E Stride, V Sboros

Physics in medicine and biology, vol. 58, IOP Publishing, 2013, p. 589



Microbubble oscillations in capillary tubes


D H Thomas, Vassilis Sboros, Marcia Emmer, Hendrik Vos, Nico De Jong

Ultrasonics, Ferroelectrics and Frequency Control, IEEE Transactions on, vol. 60, IEEE, 2013



MO-F-WAB-07: A Novel 4D CT Acquisition and Analysis Technique to Account for the Effect of Cardiac Induced Lung Tissue Motion During Free Breathing


D H Thomas, B White, S Gaudio, S Jani, P Lee, J Lamb, D Low

Medical Physics, vol. 40, American Association of Physicists in Medicine, 2013, pp. 411--411



TU-G-141-01: BEST IN PHYSICS (JOINT IMAGING-THERAPY)-A Novel 4D CT Acquisition and Analysis Technique to Generate Low Noise Artifact-Free Images at User Selected Breathing Phases


D H Thomas, B White, S Gaudio, S Jani, P Lee, J Lamb, D Low

Medical Physics, vol. 40, American Association of Physicists in Medicine, 2013, pp. 456--456



The effect of resonance on transient microbubble response; response; experimental and theoretical observations


DH Thomas, Mairead Butler, Padraig Looney, Nikos Pelekasis, Vassilis Sboros

Ultrasonics Symposium (IUS), 2012 IEEE International, IEEE, 2012, pp. 390--393



The �quasi-stable� lipid shelled microbubble in response to consecutive ultrasound pulses


DH Thomas, M Butler, T Anderson, M Emmer, H Vos, M Borden, E Stride, N de Jong, V Sboros

Applied Physics Letters, vol. 101, AIP Publishing, 2012, p. 071601



On the acoustic response of microbubbles in arteriole sized vessels


Mairead B Butler, D H Thomas, Nadia Silva, Stephen D Pye, Vassilis Sboros

Applied Physics Letters, vol. 99, AIP Publishing, 2011, p. 193702



Imaging of the ovine corpus luteum microcirculation with contrast ultrasound


Vassilis Sboros, M Averkiou, M Lampaskis, DH Thomas, N Silva, C Strouthos, J Docherty, AS McNeilly

Ultrasound in Medicine \& Biology, vol. 37, Elsevier, 2011, pp. 59--68



The acoustic scatter from single bisphere microbubbles


DH Thomas, MB Butler, A Dermitzakis, T Anderson, WN McDicken, V Sboros

Ultrasound in medicine \& biology, vol. 36, Elsevier, 2010, pp. 1884--1892



The fate of resonant and off-resonant microbubble signals in response to consecutive imaging pulses


DH Thomas, P Looney, M Butler, T Anderson, N Pelekasis

Ultrasonics Symposium (IUS), 2010 IEEE, IEEE, 2010, pp. 1712--1715



Acoustic Investigation of Attached, Single Microbubbles


Mairead B Butler, Ao Zhang, D H Thomas, Stephen D Pye, Norman McDicken, Carmel M Moran, Vassilis Sboros

Ultrasound in Medicine \& Biology, vol. 35, Elsevier, 2009, pp. S50



Single microbubble response using pulse sequences: Initial results


David H Thomas, MB Butler, T Anderson, R Steel, SD Pye, M Poland, T Brock-Fisher, WN McDicken, V Sboros

Ultrasound in medicine \& biology, vol. 35, Elsevier, 2009, pp. 112--119



Acoustic detection of microbubble resonance


DH Thomas, P Looney, R Steel, N Pelekasis, WN McDicken, T Anderson, V Sboros

Applied Physics Letters, vol. 94, AIP Publishing, 2009, p. 243902



Optical observations of microbubble oscillation in small tubes


DH Thomas, Vassilis Sboros, Marcia Emmer, Hendrik J Vos, Nico de Jong

Ultrasonics Symposium (IUS), 2009 IEEE International, IEEE, 2009, pp. 2782--2784



Optical observations of microbubble oscillation in small tubes


DH Thomas, Vassilis Sboros, Marcia Emmer, Hendrik J Vos, Nico de Jong

Ultrasonics Symposium (IUS), 2009 IEEE International, IEEE, 2009, pp. 2782--2784



The acoustic response from individual attached and unattached rigid shelled microbubbles


Mairead B Butler, D H Thomas, Stephen D Pye, Carmel M Moran, W Norman McDicken, Vassilis Sboros

Applied Physics Letters, vol. 93, AIP Publishing, 2008, p. 223906


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